From Rochester:
Take I 390 South   Pick-up I 86 East (Route 17 East)
  I 86 takes you right into Corning
   (I 390 South and I 86 East merge at the Prattsburg/Kanona exit)
   Take exit 45 towards Route 352-Riverside-Downtown Corning
   Having entered downtown, turn left on Pine St
   Turn left on Market Street.

From Binghamton:
   Take I 86 West (Route 17 West) to Corning

From Williamsport:
   Take Route 15 North
   Pick-up I 86 East (Route 17 East) at Painted Post
   Follow signs for Corning

From Jamestown:
   Take I 86 East (Route 17 East) to Corning

From Ithaca/Cortland:
   Take Route 13 South to Horseheads
   At Horseheads, pick-up I 86 West
   Follow I 86 West to Corning